At least 15 gas tankers have been burnt to ashes at Kpone tanker farm in the Greater Accra region.
The tankers reportedly belong to the oil marketing company, Goodness Energy.
The fire broke out at about 8pm Wednesday.
The Ghana National Fire Service has said it is investigating the cause of the inferno.
At least five fire tenders were needed to douse the flames which rage for more than three hours.